What Is Epithalon? Research Evidence & Profile

What Is Epithalon?

Epithalon is a short peptide research entry commonly listed under the Epithalon name. This page identifies the material as Epithalon, with amino acid count 4; synonyms Epitalon; AEDG. The Epithalon identifiers distinguish this catalogue entry from similarly named compounds, fragments, modified analogues, and multi-component formulations.

Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation.

Evidence at a Glance

0ClinicalTrials.gov query records

56PubMed query records

6Selected publications shown

Sources: ClinicalTrials.gov query · PubMed query · Retrieved 2026-10-06

Mechanism & Pharmacology

The research record for Epithalon is organized around short-peptide characterization, cellular-aging literature review, peptide stability studies, and analytical peptide profiling. For Epithalon, those subjects define the literature and analytical context of this specific research peptide; they do not establish a clinical indication, administration route, or expected outcome.

Mechanistic or pathway language defines a research scope. It does not establish that a catalogue product produces a clinical effect.

Clinical Development

Selected exact-query registry records are shown below. Desktop displays up to six; mobile displays up to three.

NCT ID / Study	Phase	Status	Context	Last registry update
No exact-match registry records were returned by the displayed query at the retrieval time.

Source: ClinicalTrials.gov search · Retrieved 2026-10-06

Selected Literature6 important records shown

Selected Literature

Selected PubMed record

Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.

Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026 Jan 1

PMID 41490200

Selected PubMed record

Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties.

International journal of molecular sciences · 2025 Mar 17

PMID 40141333

Selected PubMed record

Epithalon decelerates aging and suppresses development of breast adenocarcinomas in transgenic her-2/neu mice.

Bulletin of experimental biology and medicine · 2002 Aug

PMID 12459848

Selected PubMed record

Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.

Bulletin of experimental biology and medicine · 2003 Jun

PMID 12937682

Selected PubMed record

Effects of short peptides on lymphocyte chromatin in senile subjects.

Bulletin of experimental biology and medicine · 2004 Jan

PMID 15085253

Selected PubMed record

Epithalon inhibits tumor growth and expression of HER-2/neu oncogene in breast tumors in transgenic mice characterized by accelerated aging.

Bulletin of experimental biology and medicine · 2002 Feb

PMID 12428286

Source: PubMed search results · Retrieved 2026-10-06

Identity & ChemistryProduct-form fields

Identity & Chemistry

Compound / Blend: Epithalon
Available Specifications: 10mg, 50mg
Pack Format: 10 Vials
CAS Number: 307297-39-8
Molecular Formula: C14H22N4O9
Molecular Weight: 390.35 g/mol
Amino Acid Count: 4
Sequence: H-Ala-Glu-Asp-Gly-OH
Synonyms: Epitalon; AEDG
Physical Form: Lyophilized powder

Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation.

Source: PubChem CID 219042 · Product form must still be matched to the catalogue and batch record.

Research Tools for Epithalon

Review the selected registry records and open the module-level ClinicalTrials.gov query for the current result set.

Open Clinical Development

Use the complete NOVABIO documentation library to review currently available batch records.

Open Lab Results & COA

Storage & Laboratory HandlingDocumentation-led controls

Storage & Laboratory Handling

Confirm the exact material form, lot, supplied state and storage statement from the product label and corresponding batch documentation. Do not infer handling conditions from a different compound, strength or external clinical publication.

Regulatory Status

FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval.

Source: FDA Drugs@FDA · Checked 2026-10-06

Authoritative Data Summary

Epithalon Research Summary

Identity

Epithalon; specifications: 10mg, 50mg. Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation.

Mechanism

Evidence

0 registry records and 56 PubMed records were returned by the displayed query on 2026-10-06; counts are not quality ratings.

Regulatory context

FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval.

Epithalon is represented here by the catalogue identity Epithalon. Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation. The product record lists 10mg, 50mg as the currently available specifications. The research context is organized around this product-specific scope: The research record for Epithalon is organized around short-peptide characterization, cellular-aging literature review, peptide stability studies, and analytical peptide profiling. For Epithalon, those subjects define the literature and analytical context of this specific research peptide; they do not establish a clinical indication, administration route, or expected outcome. The synchronized searches returned 0 ClinicalTrials.gov records and 56 PubMed records for the displayed query. A registry count includes records with different designs, statuses and populations, while a publication count can include reviews, preclinical work and unrelated uses of a shared abbreviation; neither count is a quality score. For regulatory interpretation, FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval. Clinical findings apply only to the studied drug product, formulation, population and protocol. NOVABIO product specifications and batch documentation are separate catalogue records and do not inherit clinical outcomes from external studies. This profile supports identity checking, source tracing and laboratory record review; it does not certify a batch, recommend treatment, provide dosing instructions or replace current official labeling and professional judgment.

Sources: PubMed · ClinicalTrials.gov · FDA · NOVABIO product record

FAQ4 evidence-bounded answers

Epithalon FAQ

What is Epithalon?

What research records are indexed for Epithalon?

The synchronized query returned 0 ClinicalTrials.gov records and 56 PubMed records on 2026-10-06; review the linked searches because counts and record status can change.

Is Epithalon FDA approved?

FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval.

Does this page provide dosing guidance?

No. This research profile provides identity, evidence, chemistry, regulatory and documentation context without dosing or treatment instructions.

Sources, Methodology & Last Verified

Official sources: ClinicalTrials.gov, NCBI PubMed, FDA, available PubChem records, and NOVABIO product and COA records.
Query retrieved: 2026-10-06T12:08:49Z
Inclusion: Exact identity terms and traceable registry, publication, chemistry, regulatory or catalogue fields.
Limitations: Search counts can include mixed evidence types and shared-name records; individual records require direct review.
Prepared by: NOVABIO Research
Reviewed date: 2026-10-06
Editorial methodology: How NOVABIO builds Research Profiles
Corrections contact: Contact NOVABIO with the page URL and source record.