What Is KPV? Research Evidence & Profile

What Is Lysine-Proline-Valine (KPV)?

KPV is a tripeptide identified by the Lysine-Proline-Valine sequence and KPV abbreviation. This page identifies the material as KPV (Lys-Pro-Val), with amino acid count 3; synonyms α-MSH(11-13); Lys-Pro-Val. The KPV identifiers distinguish this catalogue entry from similarly named compounds, fragments, modified analogues, and multi-component formulations.

Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation.

Evidence at a Glance

0ClinicalTrials.gov query records

116PubMed query records

6Selected publications shown

Sources: ClinicalTrials.gov query · PubMed query · Retrieved 2026-10-06

Mechanism & Pharmacology

The research record for KPV is organized around tripeptide characterization, sequence-based peptide research, signaling-pathway literature, and analytical peptide workflows. For KPV, those subjects define the literature and analytical context of this specific research peptide; they do not establish a clinical indication, administration route, or expected outcome.

Mechanistic or pathway language defines a research scope. It does not establish that a catalogue product produces a clinical effect.

Clinical Development

Selected exact-query registry records are shown below. Desktop displays up to six; mobile displays up to three.

NCT ID / Study	Phase	Status	Context	Last registry update
No exact-match registry records were returned by the displayed query at the retrieval time.

Source: ClinicalTrials.gov search · Retrieved 2026-10-06

Selected Literature6 important records shown

Selected Literature

Selected PubMed record

Airway management in neuroanesthesiology.

Anesthesiology clinics · 2012 Jun

PMID 22901608

Selected PubMed record

KPV and RAPA Self-Assembled into Carrier-Free Nanodrugs for Vascular Calcification Therapy.

Advanced healthcare materials · 2024 Dec

PMID 39252648

Selected PubMed record

A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.

Acta biomaterialia · 2022 Apr 15

PMID 35245681

Selected PubMed record

International Recommendations for the Diagnosis and Management of Patients With Adrenoleukodystrophy: A Consensus-Based Approach.

Neurology · 2022 Nov 22

PMID 36175155

Selected PubMed record

Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia.

The New England journal of medicine · 2022 Mar 24

PMID 35320643

Selected PubMed record

Trial of Erythropoietin for Hypoxic-Ischemic Encephalopathy in Newborns.

The New England journal of medicine · 2022 Jul 14

PMID 35830641

Source: PubMed search results · Retrieved 2026-10-06

Identity & ChemistryProduct-form fields

Identity & Chemistry

Compound / Blend: KPV (Lys-Pro-Val)
Available Specifications: 5mg, 10mg
Pack Format: 10 Vials
CAS Number: 67727-97-3
Molecular Formula: C16H30N4O4
Molecular Weight: 342.43 g/mol
Amino Acid Count: 3
Sequence: Lys-Pro-Val
Synonyms: α-MSH(11-13); Lys-Pro-Val
Physical Form: Lyophilized powder

Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation.

Source: PubChem CID 125672 · Product form must still be matched to the catalogue and batch record.

Research Tools for Lysine-Proline-Valine (KPV)

Review the selected registry records and open the module-level ClinicalTrials.gov query for the current result set.

Open Clinical Development

Use the complete NOVABIO documentation library to review currently available batch records.

Open Lab Results & COA

Storage & Laboratory HandlingDocumentation-led controls

Storage & Laboratory Handling

Confirm the exact material form, lot, supplied state and storage statement from the product label and corresponding batch documentation. Do not infer handling conditions from a different compound, strength or external clinical publication.

Regulatory Status

FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval.

Source: FDA Drugs@FDA · Checked 2026-10-06

Authoritative Data Summary

Lysine-Proline-Valine (KPV) Research Summary

Identity

KPV (Lys-Pro-Val); specifications: 5mg, 10mg. Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation.

Mechanism

Evidence

0 registry records and 116 PubMed records were returned by the displayed query on 2026-10-06; counts are not quality ratings.

Regulatory context

FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval.

Lysine-Proline-Valine (KPV) is represented here by the catalogue identity KPV (Lys-Pro-Val). Identity fields describe the named catalogue record and must not be generalized to a different salt, counter-ion, hydrate or formulation. The product record lists 5mg, 10mg as the currently available specifications. The research context is organized around this product-specific scope: The research record for KPV is organized around tripeptide characterization, sequence-based peptide research, signaling-pathway literature, and analytical peptide workflows. For KPV, those subjects define the literature and analytical context of this specific research peptide; they do not establish a clinical indication, administration route, or expected outcome. The synchronized searches returned 0 ClinicalTrials.gov records and 116 PubMed records for the displayed query. A registry count includes records with different designs, statuses and populations, while a publication count can include reviews, preclinical work and unrelated uses of a shared abbreviation; neither count is a quality score. For regulatory interpretation, FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval. Clinical findings apply only to the studied drug product, formulation, population and protocol. NOVABIO product specifications and batch documentation are separate catalogue records and do not inherit clinical outcomes from external studies. This profile supports identity checking, source tracing and laboratory record review; it does not certify a batch, recommend treatment, provide dosing instructions or replace current official labeling and professional judgment.

Sources: PubMed · ClinicalTrials.gov · FDA · NOVABIO product record

FAQ4 evidence-bounded answers

Lysine-Proline-Valine (KPV) FAQ

What is Lysine-Proline-Valine (KPV)?

What research records are indexed for Lysine-Proline-Valine (KPV)?

The synchronized query returned 0 ClinicalTrials.gov records and 116 PubMed records on 2026-10-06; review the linked searches because counts and record status can change.

Is Lysine-Proline-Valine (KPV) FDA approved?

FDA status must be checked by exact drug product, formulation and indication; catalogue availability does not establish approval.

Does this page provide dosing guidance?

No. This research profile provides identity, evidence, chemistry, regulatory and documentation context without dosing or treatment instructions.

Sources, Methodology & Last Verified

Official sources: ClinicalTrials.gov, NCBI PubMed, FDA, available PubChem records, and NOVABIO product and COA records.
Query retrieved: 2026-10-06T12:08:49Z
Inclusion: Exact identity terms and traceable registry, publication, chemistry, regulatory or catalogue fields.
Limitations: Search counts can include mixed evidence types and shared-name records; individual records require direct review.
Prepared by: NOVABIO Research
Reviewed date: 2026-10-06
Editorial methodology: How NOVABIO builds Research Profiles
Corrections contact: Contact NOVABIO with the page URL and source record.